Abstract: In many parts of the world, structures face the very real threat of being subjected to the effects of blast induced shock waves triggered by terrorist attacks or accidental explosions for which they were not designed. The University of Ottawa’s Blast Research Group has undertaken an experimental research program to develop retrofit techniques to increase the survivability and life safety of structures subjected to blast pressures. This paper presents the preliminary findings on performance of reinforced concrete slab panels retrofitted with externally bonded CFRP sheets and subjected to simulated blast loading. Two identical 2400 x 2400 x 75 mm slabs were constructed; one slab was retrofitted with CFRP sheets, while the companion as-built slab served as the control specimen. The slabs were restrained against rotation along their sides with fixed supports. Blast loading was simulated using the University of Ottawa’s Shock Tube testing facility. The experimental response of the as-built slab is compared with theoretical response predicted using a SDOF analysis by SBEDS software available through the US Army Corps of Engineers. This comparison indicate that SBEDS over-predicts slab strength for low intensity blasts, while the predicted response for larger explosions is generally in good agreement with the experimental data. Experimental results indicate that the CFRP retrofit greatly improves the performance of reinforced concrete slabs when subjected to explosive loading.