Abstract: Despite the importance of anchorage in windows systems designed to resist terrorist attacks and accidental explosions, the design of window retention anchors has often been handled through empirical methods and testing. This paper introduces a design procedure and software implementation BRADS (Blast-resistant anchor design software) for the analysis and design of new blast-resistant glazing anchorages or for vulnerability assessment of existing anchors. The innovative design procedure can compute the required configuration of window retention anchors based on the major parameters known to influence anchorage capacity, including: substrate flexibility, glazing response, window aspect ratio, frame rigidity, the distribution of dynamic reactions, combined stresses, and anchorage boundary conditions. The results generated by BRADS were compared against shock tube testing of blast-resistant window systems conducted on three different sizes of window, retrofitted with different thicknesses of protective window film, installed into different substrates using a variable number of retention anchors and anchor spacings. The comparison indicated that BRADS can predict the magnitude and distribution of anchor forces of the tested windows with a level of accuracy suitable for the purposes of design and assessment.